BIOMIS - "Costituzione della biobanca del microbiota intestinale e salivare umano: dalla disbiosi alla simbiosi" is a collaborative project aimed at establishing the first Italian biobank of intestinal, salivary and vaginal microbiota. Microorganisms will be characterized using high-throughput meta-omic approaches. In vivo and in vitro studies will be performed, with animal models matching patients’ clinical characteristics. Therapeutic approaches will be explored, studying the efficacy of faecal microbiota transplantation (FMT) in patients with different diseases, to restore the healthy microbiome in the diseased colon, leading to symptoms resolution. Innovative capsules and faecal suspensions will be produced in order to implement new administration strategies for the FMT. The outcomes of BIOMIS will enable healthcare professionals to custom therapeutic applications by modulating patient microbiota and specific host – microbe interactions. Top-leading research and clinical centres will collaborate with private companies to streamline project objectives and open new therapeutic perspectives for several human diseases.

ROLE OF THE FOUNDATION

The Foundation ensured the compliance of the project activities with the regulatory and ethical standards and will supported the participation of the new BIOMIS biobank in the European research infrastructure BBMRI-ERI. Moreover, the Foundation defined the quality procedure to ensure the technical and scientific consistency of the activities.

FUNDED BY: PON “Ricerca e Innovazione” 2014-2020 e FSC

DURATION: May 2019 - Nov 2022

PARTNERS: